Chamber and committees

Question reference: S2W-01551

Asked by: Brian Adam, MSP for Aberdeen North, Scottish National Party
Date lodged: 16 July 2003
Current status: Answered by Tom McCabe on 13 August 2003

Question

To ask the Scottish Executive how much factor (a) VIII and (b) IX has been used in the treatment of haemophilia; what proportion of each product was synthetic and how many patients were treated using each product, in each of the last 10 years.

Answer

The details requested on the usage and type of products in each of the years from 1989-90 to 2002-03 are shown in the following tables.Details of the how many patients were treated using each product are not held centrally.Yearly Usage of Factor VIII in Scotland (IU x 10⁶)

Year	89-90	90-91	91-92	92-93	93-94	94-95	95-96	96-97	97-98	98-99	99-00	00-01	01-02	02-03
PFC FVIII	6.99	7.68	8.24	10.85	11.63	11.54	13.41	10.94	8.62	6.72	4.94	3.35	5.17	1.48
Com FVIII	1.18	0.95	2.08	1.24	0.98	0.82	1.07	1.04	0.57	0.34	0.79	0.79	0.62	0.67
r FVIII	0	0	0	0	0	0.33	0.38	3.18	6.94	8.38	13.85	16.62	15.96	23.97
Tot FVIII	8.16	8.63	10.32	12.09	12.62	12.69	14.85	15.17	16.13	15.45	19.58	20.76	21.76	26.13

Notes:PFC FVIII Factor VIII manufactured by the Scottish National Blood Transfusion Service at the Protein Fractionation Centre.Com FVIII Factor VIII purchased from a commercial manufacturer. These figures do not include recombinant factor VIII.r FVIII Recombinant factor VIII.Tot FVIII Total factor VIII usage.Yearly Usage of Factor IX in Scotland (IU x 10⁶)

Year	89-90	90-91	91-92	92-93	93-94	94-95	95-96	96-97	97-98	98-99	99-00	00-01	01-02	02-03
DEFIX	2.33	2.08	2.21	2.48	2.80	2.02	0.66	0.77	0.76	0.85	1.01	0.85	0.75	0.84
HIPFIX	0	0	0.11	0.14	0.23	0.77	2.41	1.22	0.09	0.09	0.01	0.00	0.00	0.00
Com HP9	0	0	0	0	0	0.10	0.14	2.09	3.98	3.13	1.14	0.69	0.59	0.52
r FIX	0	0	0	0	0	0	0	0.01	0.02	0.60	2.84	4.83	4.27	6.11
Tot HP9	0	0	0.11	0.14	0.23	0.87	2.55	3.32	4.09	3.82	3.99	5.52	4.86	6.63
Tot FIX	2.33	2.08	2.32	2.63	3.03	2.89	3.22	4.09	4.85	4.67	5.00	6.37	5.60	7.47

Notes:DEFIX Prothrombin complex concentrate containing factors II, IX and X manufactured by the Scottish National Blood Transfusion Service at the Protein Fractionation Centre.HIPFIX High purity factor IX manufactured by the Scottish National Blood Transfusion Service at the Protein Fractionation Centre.Com HP9 High purity factor IX purchased from a commercial manufacturer. These figures do not include recombinant factor IX.r FIX Recombinant factor IX.Tot HP9 Total high purity factor IX. These figures do not include DEFIX usage.Tot FIX Total factor IX usage including DEFIX.

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